new elaborated technique for isolation and purification of limonene from orange oil

نویسندگان

yaghoub amanzadeh

department of phamacognosy, faculty of pharmacy, tehran university of medical sciences, tehran, iran mani ashrafi

department of phamacognosy, faculty of pharmacy, tehran university of medical sciences, tehran, iran fatemeh mohammadi

department of phamacognosy, faculty of pharmacy, tehran university of medical sciences, tehran, iran

چکیده

essential oil of the orange peel which was extracted by hydrodistillation method showed 50 different mono- and sesquiterpenes on gc-ms analysis, in which limonene had the highest percentage (92.4%). due to various important uses of the compound, a method was developed for isolation and purification of limonene. in this method, for extra purification, a fractional distillation on vigreux column under 100 mm hg vacuum was used which resulted in 96.7% purity for limonene. subsequent chromatography by two different packages of silica gel and active charcoal columns resulted in 99.4% and 99.9 % purity of limonene, respectively.

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عنوان ژورنال:
iranian journal of pharmaceutical sciences

جلد ۲، شماره ۲، صفحات ۸۷-۹۰

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